ABSTRACT
Argyria is a rare cause of cutaneous discoloration due to silver deposition. We report a case of argyria occurring in a 38-year-old man due to excessive silver pill intake. He had a diffuse, bluish-gray pigmentation on his face and finger nails. ICPMS (inductively coupled plasma mass spectrometry) revealed that an excess of silver was present in the patient's blood, liver and skin tissue.
Subject(s)
Adult , Humans , Argyria , Fingers , Liver , Pigmentation , Plasma , Silver , SkinABSTRACT
Contact urticaria refers to a wheal-and-flare response which occurs on intact skin after application of a chemical. When contact urticaria is accompanied by systemic symptoms, it is known as the contact urticaria syndrome. We report a case of contact urticaria syndrome occurring in a 24-year-old nurse, due to occupational exposure to cefotiam. An open patch test showed a positive reaction to cefotiam.
Subject(s)
Humans , Young Adult , Cefotiam , Occupational Exposure , Patch Tests , Skin , UrticariaABSTRACT
BACKGROUND: A number of cytokines, growth factors and inflammatory mediators made by keratinocytes, fibroblasts and potentially other cells in the skin were shown to augment melanin production and/or melanin transfer to keratinocytes. A lot of studies were done to investigate the mechanisms. But there was no studies about sequential relationship between the suggestive factors. OBJECT: To measure the changes in expressions of ET-1, MITF, and PAR-2 after UV exposure on skin in Korean. MATERIAL AND METHOD: We established an immunohistochemical staining protocol for specimens which were obtained from UV-irradiated skin in four healthy Korean males on the 2nd, 4th, 7th days after UV irradiation. RESULT: This study reveals the sequential relationship between ET-1, MITF, and PAR-2. ET-1 was increased at day 2 and decreased at day 4 and 7. MITF increased gradually day 2, day 4, and day 7. PAR-2 increased at day 4 and increased once more at day 7.
Subject(s)
Humans , Male , Cytokines , Endothelin-1 , Fibroblasts , Intercellular Signaling Peptides and Proteins , Keratinocytes , Melanins , Melanocytes , Microphthalmia-Associated Transcription Factor , Microphthalmos , SkinABSTRACT
During pregnancy profound immunologic, metabolic, endocrine, and vascular changes occur. Because of these changes, some diseases are affected by pregnancy. These diseases can aggravate or improve during pregnancy. Lymphomatoid papulosis is a continuing self-healing eruption whose lesions are clinically benign but histologically contain malignant-appearing cells. We report a case of lymphomatoid papulosis which developed in 30-year-old pregnant woman. And we discussed the possible association between lymphomatoid papulosis and pregnancy.
Subject(s)
Pregnancy , Female , HumansABSTRACT
Unilateral nevoid telangiectasia was first described by Blaschko in 1899. Since then there have been fewer than 100 reported cases. This rarely reported disorder consists of multiple telangiectasias primarily located unilaterally in the C3-T1 dermatomes. We describe unilateral nevoid telangiectasia in 13-year-old boy with association with increased estrogen level in puberty.
Subject(s)
Adolescent , Humans , Male , Estrogens , Puberty , TelangiectasisABSTRACT
We report a case of type IIb hyperlipoproteinemia associated with xanthoma tuberosum, xanthoma planum and xanthoma striatum. Serum lipoprotein electrophoresis showed increased beta fraction and pre-beta fraction, suggesting type IIb hyperlipoproteinemia.